Wednesday, August 15, 2012

Researchers find more-effective prostate cancer drug | TopNews ...

Researchers find more-effective prostate cancer drug Researchers at Imperial College London have claimed that they have discovered a new, more-effective drug to treat prostate cancer.

The new drug named Celastrol, which is derived from a plant called Tripterygium wilfordii (Thunder God Vine), is capable of curbing p23, a protein that acts with HSP90 protein to activate prostate tumors' hormonal response.

Tripterygium wilfordii, which is already used in Chinese medicine, is a potent anti-inflammatory agent and antioxidant.

The findings of the research were reported in the latest issue of journal Molecular Endocrinology.

Study leader Dr. Charlotte Bevan excitingly said that the research was already a step closer to the clinic because drugs that suppress p23 protein, such as celastrol, had already shown promise in curbing a number of diseases like asthma and arthritis.

Speaking on the topic, Bevan added, "The next stage will be to test the effects of such drugs on prostate cancer cells in the lab."

Available figures suggest that prostate cancer is the most common types of cancer among males in the UK, with more than 34,000 males diagnosed with the condition every year.

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Source: http://topnews.net.nz/content/223871-researchers-find-more-effective-prostate-cancer-drug

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